Innovation Overground publishes new episode

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OMAHA, Neb. (August 13, 2018)—UNeMed’s tech transfer podcast, “Innovation Overground,” published this morning its latest episode, “A fistful of yardsticks.”

In the latest episode, Overground hosts Joe Runge, Tyler Scherr and Charlie Litton, discuss an inventor’s need to sometimes “innovate to innovate.” Overground crew explains that medical innovations sometimes require new measurements and models just to get to the big idea.

The episode also features a new approach to an old procedure for kidney failure, the AV fistula.

Innovation Overground was created to help promote academic innovation and the technology transfer and commercialization efforts at the University of Nebraska and beyond. The podcast intends to examine what it takes to advance academic inventions and discoveries beyond the research bench and into people’s lives as “actual things on a shelf.”

New episodes are published on Mondays, and are available on most podcast channels, including Google Play Music, iTunes, iHeartMusic, Podomatic, Spotify and Spreaker.

Use the below links to subscribe, listen to previous episodes and learn more.

Listen on Apple Podcasts
Listen on Google Play Music
Listen on iHeart Radio
Innovation Overground on Spotify
Listen to this podcast on Spreaker
Player FM
Pocket Cast
Luminary

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Innovation Overground takes on CRISPR in latest episode

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OMAHA, Neb. (August 6, 2018)—UNeMed’s tech transfer podcast, “Innovation Overground,” published this morning its latest episode, “The CRISPR episode.”

In the latest episode, Overground hosts Joe Runge, Tyler Scherr and Charlie Litton, discuss a gene editing tool, CRISPR, its popularity within science fiction and its practical uses out here in reality. The Overground crew talks about what CRISPR is, what it can and can’t do, and have some fun with rampaging mutants and superheroes.

The episode also features Easi-CRISPR a tool jointly invented at UNMC and the University of Tokai. The crew discusses how Easi-CRISPR makes genome editing remarkably better.

Innovation Overground was created to help promote academic innovation and the technology transfer and commercialization efforts at the University of Nebraska and beyond. The podcast intends to examine what it takes to advance academic inventions and discoveries beyond the research bench and into people’s lives as “actual things on a shelf.”

New episodes are published on Mondays, and are available on most podcast channels, including Google Play Music, iTunes, iHeartMusic, Podomatic, Spotify and Spreaker.

Use the below links to subscribe, listen to previous episodes and learn more.

Listen on Apple Podcasts
Listen on Google Play Music
Listen on iHeart Radio
Innovation Overground on Spotify
Listen to this podcast on Spreaker
Player FM
Pocket Cast
Luminary
 

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UNMC tops $135 million in research funding, sets new record

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University of Nebraska Medical Center researchers have set a new record – bringing in $135.6 million in research funding for fiscal year 2018, up 15.8 percent from $117 million the previous year.

Vice Chancellor Larsen

Vice Chancellor Larsen

“Kudos to our research community for their success and hard work,” said Jennifer Larsen, M.D., vice chancellor for research at UNMC. “Everyone contributed to this accomplishment. We have recruited and mentored outstanding faculty, successfully competed for large grant awards, and many people – from administrators to research technicians and coordinators – have worked hard alongside the investigators to make this happen.”

Dr. Larsen said UNMC saw increases in the total number of grants, the number of unique principal investigators, the total number of faculty on grants, the average size of grants, and the number of large grants such as center grants.

UNMC Chancellor Jeffrey P. Gold, M.D., said, “The research programs at UNMC are critical to our mission and serve as a key foundation to our definition of being a world-class academic medical center.

“This continued record-breaking research funding recognizes the excellence of our scientists, our facilities and the continued relevance of our research programs. Congratulations on another remarkable year.”

The following units saw double digit increases in their research awards: the Eppley Institute for Cancer Research (19.5 percent), the Munroe-Meyer Institute (39.3 percent), and the Colleges of Medicine (11.4 percent), Pharmacy (10.7 percent), and Public Health (63.4 percent).

Awards from federal agencies increased 15 percent overall, either as primary awards (11.8 percent; 90 percent of which came from the National Institutes of Health); or sub-awards, which include federal awards from other universities, the University of Nebraska (21 percent) or others (12 percent). U.S. Department of Defense awards through the National Strategic Research Institute increased 43 percent.

Regardless of the funding source, the $135.6 million is awarded to specific individuals for projects that cover a broad range of topics, including:

  • $2.27 million to Rob Lewis, PhD, Eppley Institute, to develop the Nebraska Center for Molecular Target Discovery & Development, which is focused on taking small molecules into new biomarkers or treatments for cancer and other diseases.
  • $2.1 million to Keely Buesing, M.D., department of surgery, for novel strategies to address en route care of warfighters who sustain lung injury.
  • $1.64 million to Surinder Batra, PhD, College of Medicine, for a multi-project grant focused on understanding pancreatic cancer metastasis.
  • $1.14 million to Tatiana Bronich, PhD, College of Pharmacy, to continue to grow and develop the Nebraska Center for Nanomedicine, strategies to transform medicines to make them more effective in reaching their target.
  • $510,000 to David Dzewaltowski, PhD, College of Public Health, for community strategies that might improve the physical activity of youth.
  • $380,000 to Christine Eisenhauer, PhD, College of Nursing-Northern Division, for a mobile technology strategy to engage rural men in losing weight.

 

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Innovation Overground podcast airs next episode

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OMAHA, Neb. (July 30, 2018)—UNeMed’s tech transfer podcast, “Innovation Overground,” published this morning its latest episode, “Tech transfer 101 & leadership.”

In the latest episode, Overground hosts Joe Runge, Tyler Scherr and Charlie Litton, discuss some behind the scene basics of technology transfer and commercialization. The crew also banters about leadership as they poke a little fun at themselves in a light-hearted 19-minute episode.

The episode also featured two UNMC innovations, including NeuroFreeze and UNeMed’s Salesforce implementation.

Innovation Overground was created to help promote academic innovation and the technology transfer and commercialization efforts at the University of Nebraska and beyond. The podcast intends to examine what it takes to advance academic inventions and discoveries beyond the research bench and into people’s lives as “actual things on a shelf.”

New episodes are published on Mondays, and are available on iTunes, Google Play Music, and Spreaker. It will soon be available on Spotify and iHeartMusic.

Current subscription options for the Innovation Overground podcast:

Listen on Apple Podcasts
Listen on Google Play Music
Listen on iHeart Radio
Innovation Overground on Spotify
Listen to this podcast on Spreaker
Player FM
Pocket Cast
Luminary
 

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UNMC solves big data problem in EHRs

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OMAHA, Neb. (July 24, 2018)—A modern genetic test for a cancer patient contains more information than ever before: Too much, in fact, for modern digital medical records.

That’s a problem. A big, big data problem. But it’s a problem with a solution at the University of Nebraska Medical Center.

New tests, particularly those genetic cancer tests, hold critical clues about the nature and ferocity of a tumor. They help doctors and patients plan treatments, and adjust for new mutations in the tumor.

But those tests don’t neatly fit into modern health records. In fact, those test results don’t fit at all. Physicians must wade through multiple file attachments, or scroll through an apparently never-ending “notes” section for the important details.

It’s like looking for a specific movie scene among a stack of old VHS tapes. That’s great for 1995, but not in today’s digital age that moves at warp speed.

The problem is that electronic health records—EHR for short—were originally created to help the billing process.

“EHRs were not built for clinical teams to use as searchable databases,” said Kelly Choi, M.D., GenomOncology’s Chief Commercial Officer. GenomOncology is a Cleveland-based firm focused specifically on all that biomedical data, or informatics that comes out of cancer gene testing and research.

GenomOncology builds powerful engines that doctors and researchers use to tease important information from things like complex genetic tests. After signing an exclusive agreement with UNMC, GenomOncology now has a way to transmit those results to a patient’s EHR, arming their doctors and care-providers with a clearer picture of their patient’s health and history.

“Most in the industry thought it wasn’t possible to pass genomic data in a discrete manner with the current infrastructure, but we were able to find a way, with the team at UNMC,” said Manuel Glynias, founder and CEO of GenomOncology.

Dr. James Campbell

The deal began with UNMC researchers Scott Campbell, PhD, and Jim Campbell, M.D., who managed to simplify the complex. They developed a way to codify and name the multitude of facts that come from cancer gene testing. It needed to be something that a doctor could quickly and easily understand.

“There’s all this new research about cancer, and none of it matters until you can determine what kind of cancer you have and what to do about it,” said Joe Runge, the business development manager at UNMC’s technology transfer and commercialization office, UNeMed. “This technology helps doctors more easily integrate all this new information.”

UNeMed, negotiated the licensing agreement, which pairs GenomOncology’s powerful engine with the Campbells’ elegant system. The system is called the Nebraska Lexicon Synoptic Pathology Reporting Module, and functions as an add-on to the most widely-used EHR terminology in the world, SNOMED CT.

“This doesn’t happen without Scott Campbell and Jim Campbell,” said Catherine Murari-Kanti, a licensing specialist at UNeMed. “But they can’t do this without GenomOnocolgy’s platform. It’s the perfect marriage.”

Dr. Scott Campbell

Dr. Scott Campbell

GenomOncology’s platform, now armed with the UNMC module, will do more than just help with diagnoses treatment plans. The system could make a dramatic impact in research, helping filter and enroll patients for clinical trials.

“There’s a lot of cool stuff going on in oncology, and I think we’re underserving the patient because we can’t identify potential patients for trials and vice versa,” Choi said.

By making the EHR a more useful database, researchers and clinicians can find potential patients or trial programs. They will no longer need to spend countless hours poring through attachment files.

“Less than 5 percent of cancer patients get enrolled in clinical trials,” Choi said. “That number hasn’t changed since the 1980s in part due to various informatics challenges. We can do a lot better than that.”

GenomOncology enables the application of genomics in oncology to improve patient care. We have applied our expertise in genomics, technology and data integration to create solutions for cancer care providers. Our solutions are end-to-end: from the data coming out of the sequencer to the bedside where oncologists make treatment decisions. Our technology streamlines workflow and creates actionable reports for pathologists. Downstream, we integrate molecular and clinical information, providing oncologists with powerful decision-support tools that enable treatment selection, patient identification for clinical trials, and a “patients-like-mine” feature for use in difficult cases – all delivered through a real-time platform. Our solutions also enable “Big Data” analysis of aggregate data to drive research and new insights.

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UNeMed hosting regional drug development conference

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OMAHA, Neb. (July 25, 2018)—A new conference will bring together about a dozen Midwestern universities with major pharmaceutical firms as a way to promote early-stage medical technologies, officials announced today.

The event is called the Midwest Drug Development Conference, and is hosted by the University of Nebraska Medical Center’s technology transfer and commercialization office, UNeMed.

The primary goal of the event is to create one event where pharmaceutical firms and investor groups can learn about the latest therapeutic technologies and startup companies. The conference is exclusively aimed at Midwestern universities, but the industrial and investors groups could span the globe.

“I really dislike the term ‘flyover country,’ but there’s no escaping that perception,” UNeMed president and CEO Michael Dixon said. “We have a ton of research talent and innovation at Nebraska, and so do our friends across the region. Putting us all under one roof gives those companies a good reason to get on a plane to see what they’re missing.”

A closer look at the 13 participating universities shows that they collectively accounted for $4.76 billion in research, produced $71.4 million in revenues for their universities, disclosed 1,783 new inventions, created 85 new startup companies, and produced 36 new products in 2016 alone.

Planners hope to build on the region’s activity, and create more opportunities for academic medical researchers. The aim is then translating those opportunities into collaborative partnerships that move innovations and discoveries into further development.

So far, the list of participating universities include Nebraska, Kansas, Kansas State, Iowa, Iowa State, Indiana, Missouri, Notre Dame, Purdue, Washington University in St. Louis, Colorado State, Oklahoma and Kentucky.

The conference will feature more than 50 presentations of Midwestern universities’ early- and middle-stage technologies and startups. The 10-minutes presentations will cover a wide scope of conditions and diseases, including cancer, infectious diseases and central nervous disorders, to name a few.

The Midwest Drug Development Conference will be held on Oct. 1-2, 2018 in the Omaha Marriott Capitol District.

Register at www.midwestdrugdevelopment.com/tickets. Through a generous sponsor, a limited number of registration fees will be waived for potential investors and biotech and pharmaceutical company representatives. Contact UNeMed to learn how to receive a waiver code.

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UNeMed launches tech transfer podcast

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OMAHA, Neb. (July 23, 2018)—UNeMed launched today its pilot episode of a planned podcast series, “Innovation Overground,” which will publish new episodes on Mondays.

The series was created to help promote academic innovation and the technology transfer and commercialization efforts at the University of Nebraska. The podcast intends to examine what it takes to advance academic inventions and discoveries beyond the research bench and into people’s lives as “actual things on a shelf.”

Listen on Apple Podcasts“We really want to tell the untold stories of innovation,” said Joe Runge, one of the podcasts’ three co-hosts and UNeMed’s Business Development Manager. “We see these stories every day, and they’re a really interesting and fun way to show people how universities—not just Nebraska—are working to improve our lives.”

Listen on Google Play MusicRunge is joined on the podcast by UNeMed licensing associate Tyler Scherr, PhD, and communications specialist Charlie Litton. The podcast is currently available on iTunes and Google Play Music. The podcast will eventually appear on Spotify after the third episode and on iHeartRadio after the fifth episode.

In the first episode, which runs about 17 minutes, the co-hosts banter about some of the more pervasive “myths” associated with tech transfer. They also discuss the idea of moving publicly funded research into things on a shelf, and point out that innovation doesn’t have to be a big idea to make a life-altering impact.

“I think what’s great about this project are the fun little nuggets we find about the innovations we discuss,” said Scherr. “This isn’t going to be a weekly innovation infomercial. Our goal here is to make these podcasts less ‘ShamWow!’ and more VH-1’s ‘Behind the Music.'”

All podcasts are expected to run about 15 minutes, and the hosts said they plan to discuss more than just Nebraska innovations. Initial podcasts, however, will discuss UNMC and UNO innovations, including Easi-CRISPR and Avert’s concussion device.

“We could make this about just Nebraska or UNMC or even just UNeMed,” Runge said. “But then that wouldn’t be very interesting to very many people. What is interesting is finding those stories and telling them in a compelling way. Plus, it helps us get Charlie out of the office.”

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NIH SBIR/STTR proposal workshop coming to UNMC

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The Nebraska Business Development Center is offering a workshop to help UNMC researchers “prepare a compelling proposal” for the National Institutes of Health’s Small Business Innovation Research and Small Business Technology Transfer grants.

The two-day workshop will be in room 1005 of the Durham Research Center beginning at 8 a.m. on July 25. The workshop concludes on July 26, and cost is $45. Purchase tickets and learn more here.

Attendees can expect to learn:

  • Current information on the SBIR/STTR program
  • Strategies for targeting proposals to meet the mission and requirements of NIH
  • Step-by-step instruction on how to write each section of a proposal
  • Elements of a successful commercialization plan
  • How to meet the reviewers’ expectations
  • Navigating the process of submission
  • Common problems and pitfalls, and how to avoid them

The workshop will be presented by Shannon Bass, a professional consultant with BBC Entrepreneurial Training and Consulting. According to its website, BBCetc is Michigan-based consulting firm that advises “clients in the areas of funding eligibility and proposal development, commercialization and business planning, and grant and contract management.”

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UNMC scientists play key role in significant cancer breakthrough

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Genome-editing technology could reprogram T cells to allow them to better fight cancer cells

by Tom O’Connor, UNMC

OMAHA, Neb. (July 12, 2018)—Two University of Nebraska Medical Center scientists and their novel Easi-CRISPR genome-editing technology have contributed to a significant breakthrough in the fight against cancer.

The discovery may lead to new and safer treatments for autoimmune and other diseases, including rare inherited disorders.

From left are Channabasavaiah Gurumurthy, PhD, and Rolen Quadros.

The two UNMC scientists – Channabasavaiah Gurumurthy, D.V.M., PhD, associate professor of developmental neuroscience at the Munroe-Meyer Institute, and Rolen Quadros, transgenic researcher in the Mouse Genome Engineering Core Facility – collaborated with researchers at the University of California, San Francisco (UCSF) to develop a technique in which they genetically reprogrammed T cells, the body’s foremost immune system fighter, to find and destroy cancer cells in mice.

The new method, described in the July 11 issue of Nature, offers a robust molecular “cut and paste” system to rewrite genome sequences in human T cells without using viruses to insert the DNA.

The collaboration began more than two years ago when Dr. Gurumurthy met Alex Marson, M.D., PhD, associate professor of microbiology and immunology, UCSF, and principal investigator of the study, at a scientific conference where they discussed the idea of using the Easi-CRISPR method to engineer T cells.

Theo Roth, a student pursing M.D. and PhD degrees in UCSF’s Medical Scientist Training Program and first author on the study, tested the idea and then did a series of other technical improvements to efficiently engineer T cells.

Before this breakthrough, numerous attempts by many researchers to place long sequences of DNA into T cells had not been effective. “The typical success rate of inserting longer DNA sequences into T cells is about one percent or less,” Dr. Gurumurthy said.

“Easi-CRISPR provided us one of the ways to develop an efficient strategy to insert longer DNA cassettes into T cells,” he said. “With this method, we can take a cancer patient’s blood cells, isolate the T lymphocytes, manipulate the genome and train them to kill cancer cells, then transfer them back into the patient. Engineering a patient’s own T cells to find and kill cancer cells would be the most effective way of treating cancer.”

T cells are naturally attracted to an antigen on the cancer cell surface. Genetic engineering turns those cells into super cancer cell killers.

To demonstrate the new method’s versatility and power, the researchers used it to repair a disease-causing genetic mutation in T cells from children with a rare genetic form of autoimmunity and also created customized T cells to seek out and kill human melanoma cells.

Viruses cause infections by injecting their own genetic material through cell membranes, and since the 1970s, scientists have exploited this capability, stripping viruses of infectious features and using the resulting “viral vectors” to transport DNA into cells for research, gene therapy and in a well-publicized recent example, to create the CAR T-cells used in cancer immunotherapy.

T cells engineered with viruses are now approved by the U.S. Food and Drug Administration to combat certain types of leukemia and lymphoma. But, creating viral vectors is a painstaking, expensive process, and a shortage of clinical-grade vectors has led to a manufacturing bottleneck for both gene therapies and cell-based therapies.

Even when available, viral vectors are far from ideal, because they insert genes haphazardly into cellular genomes, which can damage existing healthy genes or leave newly introduced genes ungoverned by the regulatory mechanisms that ensure that cells function normally.

These limitations, which could potentially lead to serious side effects, have been cause for concern in both gene therapy and cell therapies such as CAR T-based immunotherapy.

“There has been 30 years of work trying to get new genes into T cells,” Roth said. “Hundreds of labs can now engineer these cells. They can work with increasingly more complex DNA sequences and try more possibilities, which will significantly speed up the development of future generations of cell therapy.”

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Nebraska ranks among world’s top 100 in earning U.S. patents

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LINCOLN, Neb. (July 11, 2018)—A new report ranks the University of Nebraska among the top 100 universities worldwide in earning U.S. patents to protect innovative research and discoveries.

The report was released this summer by the National Academy of Inventors and the Intellectual Property Owners Association. It ranks Nebraska 70th globally for the number of U.S. patents awarded to NU’s technology transfer offices – NUtech Ventures at the University of Nebraska-Lincoln and UNeMed Corp. at the University of Nebraska Medical Center and the University of Nebraska at Omaha.

By earning patents, NUtech Ventures and UNeMed can work effectively with NU faculty, staff and students to bring research to the marketplace, resulting in local startup companies, new jobs and university-licensed products that grow the economy and improve quality of life in Nebraska and beyond.

Dr. Bounds

“To be named in the company of some of the world’s leading research universities is one more sign that the University of Nebraska is on a remarkable trajectory in growing our state for the future,” NU President Hank Bounds said. “The good work of our technology transfer offices is helping our talented faculty and students generate broad impact from their innovations – a benefit not just to our economy, but to the people whose lives are ultimately transformed by research born at the University of Nebraska.”

Bounds noted that the university represents a $3.9 billion annual economic engine for the state, generating 11,000 new graduates each year who meet critical workforce needs in agriculture, healthcare, teaching, business, STEM and other areas. NU research, which alone has an almost $400 million annual economic impact, also continues to earn recognition. An independent report last year ranked the University of Nebraska in the top 16 percent nationally for its success in commercializing faculty work in areas like agriculture, engineering and medicine for economic growth.

The new report’s rankings are based on 2017 patent data from the U.S. Patent and Trademark Office. Nebraska’s 37 patents include a robotic surgical device and a structural concrete formula to shield buildings from electromagnetic pulse attack.

After securing a patent, the university brings research to market by licensing technology to existing companies or university startup companies. Most university technology is considered early-stage and requires additional research and development.

For example, the structural concrete formula – developed by College of Engineering faculty Christopher Tuan and Lim Nguyen – is licensed to a U.S. company developing buildings that shield from electromagnetic pulses. The robotic surgical device is licensed to university startup company Virtual Incision Corp., led by UNL engineering professor Shane Farritor and UNMC surgeon Dmitry Oleynikov, with the goal of making surgeries more affordable and less invasive.

“We look forward to these newly patented technologies impacting society over the next several decades as they are commercialized,” said Brad Roth, executive director of NUtech Ventures. “Together with UNeMed, our offices are committed to protecting the University of Nebraska’s intellectual property as a critical step in moving innovations from the lab to the marketplace.”

UNeMed President and CEO Michael Dixon said: “The innovations described in these patents not only have the chance to significantly improve health care, but also form the backbone of the many new startup companies that create jobs and wealth at a local level.”

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Food for thought: UNO capstone program can drive UNMC innovations

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Sachin Pawaskar (left) and Thang Nguyen chat shortly before UNO’s IS&T Capstone presentation on June 1, 2018. The project was the realization of WeChart, Nguyen’s invention of a more efficient way to teach nursing students better clinical charting skills.

by Charlie Litton, UNeMed | June 18, 2018

Nourish an invention with a robust diet of diverse thoughts and competing ideas. Go ahead.

Maybe that sounds dangerous. But diversity of thought is a super-food for those delicate innovations as they embark on what will be an absolutely brutal journey.

It’s some tough love, to be sure, but do that and remarkable things can happen.

Maybe you would rather swaddle an idea in bubble wrap and wait for the phone to ring? There’s a word for that. It’s called neglect. All you’ll likely do then is watch that idea grow old, wither and die.

It happens. It doesn’t even have to be anyone’s fault, either. It’s just the dark side of innovation that happens everywhere. Sometimes there just isn’t enough oxygen to go around.

An ER nurse, Thang Nguyen, saw it happening to one of his ideas. As one of the more innovative people at the University of Nebraska Medical Center, most of his ideas come right out of the clinic. He has a long list of better, more efficient ways to do things like washing debris from wounds and helping patients breathe.

Just like any prolific inventor, Thang finds that sometimes those ideas work and sometimes they don’t. And, like too many clever ideas and better ways, sometimes they never get a real chance to fail or succeed.

One of Nguyen’s ideas—a software program to help nursing students learn the arcane art of charting patients in real time—was heading down a path toward obscurity.

Tapping new resources

Thang’s idea: A new way to train student nurses without risking patient safety or privacy. Medical schools don’t often have a lot of resources that involve advanced coding and application design.

Except, it turns out, they actually did: Right down the road at UNO’s Peter Kiewit Institute, a seven-minute drive with bad traffic. PKI is home to the University of Nebraska Omaha’s College of Information Science and Technology and the University of Nebraska-Lincoln’s College of Engineering.

“There’s a lot of talent here at PKI that no one at UNMC even knows about,” Nguyen said.

Creating that well-balanced meal of innovation super food is not that hard. It turns out, the first, most important step is just getting the right people in the same room. What Nguyen really needed wasn’t another person in healthcare. What he needed was someone completely removed from healthcare. He needed a software engineer.

They have those in spades at UNO’s College of Information and Science Technology, or IS&T for short. They also make some serious hay with a capstone program where IS&T grad students develop concepts and ideas into actual things. Working prototypes ready for full-scale testing and, in some cases, widespread use.

Nguyen’s idea, called WeChart, lay dormant for four years. Then it joined the capstone program.

Working with UNO, Nguyen said he got more “accomplished in one semester than we did in the previous four years.”

It took a full academic year and two teams of students, but Nguyen now has a final product that, once upon a time, only lived in his imagination. It now lives in the real world.

And it will be used in the real world. UNMC’s emergency medicine department will train their student nurses with it. If all goes well, we might see other teaching hospitals and medical schools adopt the charting training program.

That’s great. Wonderful, in fact.

The bigger picture

For my money, the University of Nebraska—and other similar institutions, if they’re paying attention—should be excited about a more important prototype. I’m talking about the relationship forged between two disparate departments and two wildly different campuses.

“Medical people think one way,” Nguyen said, “a software engineer thinks one way…We should not forget that we are there to solve one central problem even if there are multiple ways of looking at it.”

For Nguyen, the “problem” of the hour was too-common charting errors from inexperienced and poorly trained young nurses. His WeChart application is one solution. We’ll find out real soon if that solution works like we all hope it does.

But there are bigger problems. Unknown problems. Problems the University of Nebraska can identify and solve, if the right people can get together.

“Why can’t we be a powerhouse,” asked the capstone program leader, Sachin Pawaskar, PhD, a research technology fellow at IS&T. “I think we have that potential.”

Sachin Pawaskar, leader of UNO’s IS&T Capstone program, addresses the gathering following his team’s WeChart presentation on June 1, 2018.

Pawaskar, who also holds an MBA, made it clear the WeChart project was critically important for the capstone program. He wanted a “showcase of what a successful partnership and relationship could be.”

That showcase will be on full display on campus at UNMC in the coming semesters as young nursing students put WeChart through the paces.

Nguyen’s idea will finally get the chance to sink or swim on its own merits, which is all anyone can really ask.

But more than that, UNMC and UNO now have a buffet line that can fuel some innovative ideas across a treacherous divide—the chasm between the sketch of a promising concept and a final product that actually makes life better.

“I really think that the healthcare area is just set up for an IT revolution,” Pawaskar said shortly after his students presented their WeChat project to Nguyen and dozens of others. Pawaskar added: “I really feel that healthcare can be totally revolutionized if we can incorporate IT at the right places at the right levels…It’s not any silver bullet, but there’s so many things you can do.”

Nguyen nodded: “And the best part? All the pieces are already here.”

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Scherr promoted to full-time licensing position

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Tyler ScherrOMAHA, Neb. (May 15, 2018)—Tyler Scherr, PhD, has been promoted from intern to a full-time licensing associate position with UNeMed, the technology transfer and commercialization office at the University of Nebraska Medical Center and the University of Nebraska at Omaha.

“We are incredibly fortunate to add the kind of rare skills and experience that Dr. Scherr brings to the team,” UNeMed president and CEO Michael Dixon said. “In addition to having a highly successful graduate research career, Dr. Scherr is an entrepreneur that understands the challenges and benefits of developing new ideas into products that can have a positive impact on healthcare.”

The promotion and full-time status expands his role of evaluating, marketing, and seeking partnerships for new inventions, cures, treatments and medical devices developed at UNMC and UNO. Dr. Scherr first joined UNeMed as a part-time intern in 2017.

UNeMed’s mission is to help UNMC and UNO researchers, faculty and staff move innovations and ground-breaking discoveries beyond the laboratory and into the marketplace. Dr. Scherr joins UNeMed’s talented stable of licensing experts who work every day to advance the University’s new discoveries into the future cures, treatments and products that might one-day affect millions around the world.

“The past year-and-a-half at UNeMed has been one of tremendous personal and professional growth,” Dr. Scherr said. “I’m deeply honored to accept this position, and I’m excited to continue working with UNMC’s and UNO’s gifted inventors and entrepreneurs.”

A native of Aberdeen, South Dakota, Dr. Scherr is the son of Dave Scherr and Liz Cox. He is a 2011 graduate of the University of Nebraska-Lincoln with an undergraduate degree in Biological Systems Engineering. Dr. Scherr received his doctorate in Biomedical Research from UNMC in December of 2016.

Dr. Scherr’s technology portfolio:

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Scherr, Zuniga featured in recent ‘Consider This’

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UNO researcher Jorge Zuniga, PhD—seen here during an Innovation Week event last October—holds up a cybernetic prosthetic hand, which he created almost entirely with 3D printers.

UNO researcher Jorge Zuniga, PhD—seen here during an Innovation Week event last October—holds up a cybernetic prosthetic hand, which he created almost entirely with 3D printers.

OMAHA, Neb. (April 17, 2018)—Tyler Scherr, PhD, a licensing associate at UNeMed, and Jorge Zuniga, PhD, a biomechanics expert at the University of Nebraska at Omaha’s biomechanics department, anchored a recent three-person panel on a local news program, “Consider This.”

The episode aired on Nebraska’s PBS affiliate, NET, and focused entirely on the marvels of 3D printing or additive manufacturing. The program covered a brief history of 3D printing and examined some of its wider applications before diving into current and even future applications.

Tyler Scherr, PhD

Dr. Scherr

Before joining UNeMed, Dr. Scherr played a large role in bringing 3D printing to the University of Nebraska Medical Center. While pursuing his doctorate in biomedical research, he co-founded UNMC’s 3D Maker’s Club.

Dr. Zuniga has gained international notoriety for his work creating affordable prosthetic limbs for children. His innovative use of 3D printing has made prosthetic devices accessible to countless children throughout the world. Much of his work is “open sourced” through his philanthropic project, Cyborg Beast. Many of his products—3D printing files—are largely available to anyone at little or no cost.

James Pierce, a graduate assistant in Dr. Zuniga’s lab, was also on the panel. Pierce is the co-founder of one of Omaha’s first 3D printing ventures, Kül 3D. Cathy Wyatt hosted the program.

“Consider This” is a half-hour weekly program produced by UNO Televeision and the UNO College of Communication, Fine Arts and Media.

Watch the entire episode here or follow this link: https://netnebraska.org/media/media.php?bin=NET&vidgroup=50005871

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Applications now open for 2018 Tech Transfer Boot Camp

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OMAHA, Neb. (May 9, 2018)—The 2018 Technology Transfer Boot Camp is scheduled for Aug. 6-10, UNeMed announced today.

Entering its fourth year, the Tech Transfer Boot Camp is aimed at scientists and students that are interested in what it takes to commercialize a new invention or discovery. The week-long event can also serve as fast-track toward an alternate career in science as a technology transfer professional.

The training program helps scientist gain a wide range of skills and experience that match their scientific knowledge and training.

The program will focus on several key areas relevant to a successful career in technology transfer, including:

  • Invention evaluation
  • Intellectual property law
  • Marketing and commercialization
  • Contract negotiation

UNeMed’s Tech Transfer Boot Camp will dive deeper than simple lectures. Topics wills be explored with hands-on activities meant to teach, correct and reinforce new skills and abilities.

Anyone within the University of Nebraska system is encouraged to apply and participate free of charge, but space is limited. People who aren’t affiliated with the University of Nebraska are also welcome, but will be charged $200 upon acceptance.

Applications will be accepted through Monday, July 30, and will be reviewed in the order they are received until all spaces are filled.

Use the embedded form below or apply here.

More information about the application process and requirements can be found at https://www.unemed.com/about-us/join-our-team#bootcamp.

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Taconic inks license deal for Easi-CRISPR

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Schematic of Easi-CRISPR

Schematic of Easi-CRISPR

RENSSELAER, N.Y. (April 23, 2018)—A technology developed in part at the University of Nebraska Medical Center was signed to a non-exclusive licensing deal that will bring Easi-CRISPR to the market.

Taconic Biosciences announced the agreement in a press release late last week, and indicated they would use the technology to genetically engineer mouse models for research purposes.

“Easi-CRISPR is the next progression of the revolutionary CRISPR/Cas technology,” John Crouse, vice president of scientific services for Taconic, said in the press release. “In an industry where time is a precious resource, access to this technology underscores Taconic’s commitment to providing our customers with the best solutions.”

The Easi-CRISPR technology could reduce research project timelines by six months, Crouse said.

A product of a collaboration between Channabasavaiah Gurumurthy, PhD, at UNMC and Masato Ohtsuka, PhD, at Tokai University in Japan, Easi-CRISPR dramatically improves the efficiency of genetic splicing. Recent headlines—and science-fiction plot lines—have featured CRISPR for is remarkable ability to precisely cut genetic code. What CRISPR cannot do very well, however, is insert or replace the genetic material.

Easi-CRISPR is that solution, providing research scientists the ability to produce genetically modified mice. That will help scientists better understand or possibly even better treat a multitude of diseases including various forms of cancer.

“The discovery of CRISPR hints at products and services that are now possible with Easi-CRISPR,” said Joe Runge, licensing specialist at UNeMed. “We’re over the moon that Taconic is the first of many to start making those possibilities real.”

Taconic is a fully-licensed provider of rodent model generation services and has over 20 years of model design experience. The company provides gene inactivation, gene mutation or replacement, transgene expression, RNAi, and gene editing via CRISPR/Cas9, pronuclear injection, and homologous recombination technologies.

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Free seminar planned: ‘Leveraging Intellectual Property for Success’

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MArk Radtke

Mark Radtke

OMAHA, Neb. (April 5, 2018)—A free seminar covering the importance of intellectual property for startups, small businesses, independent inventors, students and entrepreneurs will be held at the University of Nebraska at Omaha on Monday, April 16, 2018.

Hosted by UNO’s Nebraska Business Development Center, Mark Radtke of the United States Patent and Trademark Office, will deliver “Leveraging Intellectual Property for Success.” Radtke is the Assistant Director of the Rocky Mountain Regional USPTO. He will also be available for one-on-one meeting and small group discussions immediately following the presentation.

The talk is planned for 2-4 p.m. in the Mammel Hall auditorium at UNO’s College of Business Administration at 6708 Pine Street. Free parking will be availing in Lot 5 from 1-6 p.m.

The seminar is free and open to the public.

Any questions should be directed to Wei Jing of the Nebraska Business Development Center at wjing@unomaha.edu.

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