Virtual Incision tests surgical robots in humans

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UNL Communications

UNMC surgeon Dmitry Oleynikov (left) and UNL engineer Shane Farritor test a surgical robot prototype during a recent trial in Omaha. Their collaboration created a startup company, Virtual Incision, which hopes to make major surgery—like a bowel resection—a laparoscopic procedure.

UNMC surgeon Dmitry Oleynikov (left) and UNL engineer Shane Farritor test their surgical robot prototype during a trial several months ago in Omaha. Their collaboration created a startup company, Virtual Incision, which hopes to make major surgery—like a bowel resection—a laparoscopic procedure.  (Photo/Charlie Litton)

LINCOLN, Neb. (March 1, 2016)—Virtual Incision Corp., a company founded by faculty at the University of Nebraska-Lincoln and the University of Nebraska Medical Center, has announced the successful first-in-human use of its miniaturized robot-assisted surgical device.

The device is designed for colon resection, a procedure to treat patients with lower gastrointestinal diseases including diverticulitis, pre-cancerous and cancerous lesions of the colon, inflammatory bowel disease and colon polyps that are too large to be removed endoscopically.

“To the best of our knowledge, this is the first time an active miniaturized robot has performed complex surgical tasks with the robot inside a living human, which is a significant milestone in robotics and in surgery,” said Shane Farritor, a UNL professor of mechanical engineering who is Virtual Incision’s co-founder and chief technical officer.

The robot-assisted colon resection procedures were completed in Asunción, Paraguay, as part of the safety and feasibility trial for the technology. The surgeries were successful and the patients are recovering well, according to a news release from the company.

“Virtual Incision’s robot-assisted surgical device achieved proof-of-concept in highly complex abdominal procedures,” said head surgeon Dmitry Oleynikov, chief of minimally invasive surgery at UNMC and co-founder of Virtual Incision.

“Additionally, we verified that our extensive regimen of bench, animal, cadaver, biocompatibility, sterilization, electrical safety, software, human factors and other testing enabled the safe use of this innovative technology.”

Unlike today’s large, mainframe-like robots that reach into the body from outside the patient, Virtual Incision’s robot platform features a small, self-contained surgical device that is inserted through a single midline umbilical incision in the patient’s abdomen. Virtual Incision’s technology is designed to utilize existing tools and techniques familiar to surgeons, and does not require a dedicated operating room or specialized infrastructure. Because of its much smaller size, the robot is expected to be significantly less expensive than existing robotic alternatives for laparoscopic surgery. Virtual Incision’s technology promises to enable a minimally invasive approach to surgeries performed today with a large open incision.

The robot-assisted surgical device is investigational, and not commercially available. John Murphy, Virtual Incision’s CEO, said robot-assisted surgical are beneficial, but existing surgical robots have limitations that prevent pervasive use during certain surgeries, such as colon resection. The firm will build upon the positive completion of the feasibility study, as it works toward clearance for the system in the United States.

More than two million patients undergo colon resection procedures globally each year. About two-thirds of these procedures are performed via a completely open surgical procedure involving an 8- to 12-inch incision and up to six weeks of recovery time. Because the procedure is complicated, existing robot-assisted surgical devices are rarely used for colon resection surgeries, and manual laparoscopic approaches are only used in a third of cases.

In January, Virtual Incision and Nebraska Innovation Campus announced that the firm would be locating its headquarters at the new campus.

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UNeMed overhauls web design

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UNeMed Logo, two color — 25th Anniversary

OMAHA, Neb. (March 1, 2016)—UNeMed officially unveiled today an improved and updated website that features a more modern design while adding significantly more useful information for all UNMC personnel.

The most obvious change to the website are the visible design improvements, which includes a stylized logo that commemorates UNeMed’s 25th anniversary. The altered logo adds texts that read “25TH ANNIVERSARY” and “technology transfer for UNMC since 1991.”

UNeMed was officially incorporated on September 11, 1991, but will celebrate the milestone throughout the year with periodic features and events.

Built in conjunction with UNeMed’s 25th Anniversary, the redesigned website’s simplified interface should make finding important information quicker and easier. In particular, the new design improves the quality and presentation of UNeMed’s technology pipeline, which includes all manner of devices, tools, new drugs and other innovations and discoveries developed at UNMC.

The overhaul was intended to enhance the user experience with an upgraded interface that was more intuitive and streamlined for easier use. The design was also simplified in response to the growing use of mobile technology which often requires a user’s data plan to stream information to their devices. The new website is now “lighter,” which should require less data and decrease load times.

UNeMed always welcomes feedback and new ideas for added or improved web features. Submit our ideas or suggestions to unemed@unmc.edu or call at 402-559-2468.

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First-ever Omaha Startup Week is March 21-26

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OMAHA, Neb. (Feb, 12, 2016)—This March the first-ever Startup Week will be held in Omaha at a price that can’t be beat: Free.

According to the event website, Startup Week is a five-day series of events to celebrate the Omaha startup community, and it intended to “build momentum and opportunity around entrepreneurship.”

The event is still in the early planning stages, but people who sign up at the website will receive updates and notification when event registration opens.

According to a report at Silicon Prairie News, the Startup Week is expected to host more than 60 different events with about half of them organized into five separate tracks: youth, founder, corporate innovation, technology and marketing and sales.

Read Silicon Prairie’s full coverage here.

startupweek

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Dixon testifies before state committees on pro-business bills

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by Charles Litton, UNeMed

LINCOLN, Neb. (Feb. 3, 2016)—UNeMed president and CEO Michael Dixon testified before Nebraska’s Executive Board of the Legislative Council Tuesday in favor of two bills currently before Nebraska’s 104th Legislature.

WEB_michael_dixon_2014Both bills deal with promoting, supporting and growing start-up and small businesses in the state. For more details of the hearing, see the Lincoln Journal-Star’s coverage here.

The Executive Board opened its afternoon committee hearing with the introduction of LB987 from State Sen. Adam Morfeld of Lincoln. The bill calls for the creation of a steering committee to study Nebraska’s bioscience economy, and proposes to create a strategy for continued growth, development and commercialization of Nebraska discoveries and innovations.

The bill adds to similar economic development measures, such as the Talent & Innovation Initiative, which includes the Business Innovation Act. Those measures have dramatically improved Nebraska’s biotech business climate in recent years, but more work can be done, Dixon said.

“It’s crucial that we not rest on our laurels and become complacent,” he told the committee.

The bill would require the committee to produce its report before the close of the first 105th legislative session next year.

Dixon, who testified on behalf of the University of Nebraska, concluded his remarks to the committee: “At UNMC we have a stand. We lead the world in transforming lives to create a healthy future through extraordinary care, discovery and learning.

“When we take that stand, it means we don’t rest until we transform lives and have a significant impact on health. It isn’t just about getting grants or publishing papers or training students.

“To accomplish that stand we are driven to develop our discoveries and to make sure they have a significant impact not only on the health of all Nebraskans, but the world.”

Dixon also later testified before the same committee in favor of LB1083, the Next Generation Business Growth Act.

The Next Generation Business Growth Act, introduced by Sen. Matt Williams of Gothenburg, would create a Venture Development and Innovation Task Force that will “develop a statewide strategic plan to cultivate a climate of entrepreneurship and innovation.” The task force would study and review current and previous state programs, outline best practices in other states and perform an economic impact analysis of the Business Innovation Act.

Dixon’s testimony was related to his role as Chair of the Board for Invest Nebraska Corporation, the state’s public-private venture capital entity.

He is expected to testify again today on behalf of Invest Nebraska before the Appropriations Committee in favor of LB1028, which would extend the term and funding of the Business Innovation Act.

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Submit new inventions through the UNMC app

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SubmitNINOMAHA, Neb. (January 20, 2016)—Submitting a new invention to UNeMed just got a little easier.

A new feature on UNMC’s mobile app now allows any user to quickly submit an idea to UNeMed. The UNMC app entirely free, and is available on both Apple and Android platforms. UNeMed welcomes all ideas, inventions and discoveries from any UNMC faculty, students and staff.

To submit an idea, open the application, and select the light-bulb icon which is marked as “Ideas.” Your native browser will open, then choose “Submit an Idea to UNEMED” from the drop-down menu at the top of the screen.

Fill out the form fields asking about the idea, your name and email address. It is extremely important to include your name and contact information, or we will not be able to help.

Finally, select the “submit” button.

Once UNeMed receives the idea, we will have an early record about when the idea was conceived and can begin our process of evaluating and protecting the invention. One of our licensing managers will contact you within days to gather additional details and walk you through the remaining process.

If you prefer to submit a higher level of detail about your idea or invention, we recommend using our standard form.

The purpose of the form is to generate a written, dated record of your invention and to provide information from which the patent potential and commercial potential of your invention can be evaluated. The University needs this documentation to comply with most industrial contract requirements and the U.S. federal laws and regulations concerning grants and contracts.

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Virtual Incision LLC to locate at Nebraska Innovation Campus

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UNL Communications

UNMC surgeon Dmitry Oleynikov (left) and UNL engineer Shane Farritor test a surgical robot prototype during a recent trial in Omaha. Their collaboration created a startup company, Virtual Incision, which hopes to make major surgery—like a bowel resection—a laparoscopic procedure.

UNMC surgeon Dmitry Oleynikov (left) and UNL engineering professor Shane Farritor test a surgical robot prototype during a recent trial in Omaha. Their collaboration created a startup company, Virtual Incision, which hopes to make major surgery, like a bowel resection, a laparoscopic procedure.

LINCOLN, Neb. (Jan. 15, 2016)—Nebraska Innovation Campus has announced a new partner. Dan Duncan, executive director of NIC, said today that Virtual Incision Corp. will move into space on campus in early 2016.

Virtual Incision is a startup company founded by faculty members at the University of Nebraska Medical Center and University of Nebraska-Lincoln. The firm is developing a first-of-its-kind, miniaturized robot for abdominal surgical procedures.

“Virtual Incision is NIC’s first medical device company and will hopefully pave the way for more to follow,” Duncan said.

Virtual Incision’s robots for procedures such as colon resection are much smaller and less expensive than current robots. The robots are fully inserted into the abdomen via an umbilical incision, which reduces the invasiveness of the procedure. A surgeon at a bedside console controls the robot.

In 2006, propelled by the knowledge that colorectal and lower gastrointestinal procedures are some of the fastest-growing procedures in the United States, Dmitry Oleynikov, professor of surgery at UNMC, and Shane Farritor, professor of mechanical engineering at UNL, founded Virtual Incision. CEO John Murphy, who is located in Pleasanton, California, joined the team in 2012.

“Virtual Incision is very excited to become part of the culture on Nebraska Innovation Campus,” Farritor said. “We are glad we are associated with the University of Nebraska and have a place where our company can grow.”

The company expects to connect with students, faculty and the university — including through internships for students, student job opportunities and opportunities connected to Nebraska Innovation Studio.

NIC is a research campus designed to facilitate new and in-depth partnerships between the university and private-sector businesses. At full build-out, NIC will be a 2.2-million square-foot campus with uniquely designed buildings and amenities that inspire creative activity and engagement, transforming ideas into global innovation. For more information, visit https://www.innovate.unl.edu.

Tetrad Property Group is the private-sector development partner for NIC. Tetrad provides a full range of development services for the campus, including master planning, construction management, leasing and property management. For more information, visit https://www.tetradpropertygroup.com.

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The year in review: Highlights from 2015

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by Charles Litton, UNeMed | Jan. 11, 2016

Before moving forward it’s often useful to pause for a moment and reflect on the year that was. Here’s a review of some of the most important stories, developments, most popular posts and other highlights from UNeMed in 2015:

1. Kielian drives Innovation Week to the top

UNMC Professor of Pathology Tammy Kielian, PhD, (left)—seen here with doctoral student Megan Bosch—is UNeMed's 2015 Innovator of the Year for work against Juvenile Batten Disease and biofilm infections.

UNMC Professor of Pathology Tammy Kielian, PhD, (left)—seen here with doctoral student Megan Bosch—is UNeMed’s 2015 Innovator of the Year for work against Juvenile Batten Disease and biofilm infections.

Our annual celebration of UNMC’s innovative research is always a popular corner of the UNeMed website, but this year Innovation Week seemed to burn a little brighter than before. It can’t be a coincidence that we also crowned Tammy Kielian, PhD, as the 2015 Innovator of the Year. One of our most popular blog posts, “The trouble with fighting rare diseases,” announced a licensing agreement with Abeona Therapeutics to further develop Dr. Kielian’s work on Juvenile Batten Disease. Dr. Kielian, who was also named the 2012 Emerging Inventor, is pursuing two lines of approach for the disease: One uses an existing class of drugs as a new treatment option, and the other is a gene therapy strategy that has potential as a cure.

2. Virtual Incision raises $11.2 million

VIC-Media-1-1024x683It was a big year for one of our startups, Virtual Incision, a surgical robotics company built out of a collaboration between UNMC surgeon Dmitry Oleynikov, M.D., and UNL robotics engineering professor Shane Farritor, PhD Virtual Incision is focusing its work on making colon resection surgery—where a piece of damaged or diseased colon is removed—a minimally invasive procedure. In 2015 the company raised more than $11.2 million in the opening round of investing and landed a prestigious robotics award. Then, in case all that wasn’t enough, Drs. Oleynikov and Farritor also scored a $2.8 million grant from the U.S. Army to continue research on robotic telesurgery.

3. License deal opens doors

Everyone around here was excited about the new licensing deal signed with local software and analytics firm H4 Technology—and not just for the UNMC invention they were helping develop. The bigger picture of the H4 agreement points toward future collaborations that could develop other UNMC inventions, presuming all goes according to plan with the current deal. The current agreement is about further development of a data-management program for preventing and treating pressure ulcers, also known as bed sores.

4. UNeMed completes first Tech Transfer Boot Camp

Grad students Richard Nelson and Simarjeet Negi look on during a session of UNeMed's first Technology Transfer Boot Camp, a week of imersive training sessions that dove into the commercialization of biomedical science.

Grad students Richard Nelson and Simarjeet Negi look on during a session of UNeMed’s first Technology Transfer Boot Camp, a week of imersive training sessions that dove into the commercialization of biomedical science.

UNeMed takes seriously the educational component of its mission, and helping young scientists expand their skills into the realm of technology transfer is right in our wheel house. It’s well-known that the number of opportunities for scientists in academia continue to shrink, and a growing number are looking beyond the bench for alternate career opportunities. In June 2015 UNeMed helped some of those scientists when it offered for the first time a week-long crash-course on technology transfer and commercialization. UNeMed is already planning the 2016 Boot Camp, and expects it to continue for years to come.

5. Make yourself uncomfortable, on purpose

WEB_amanda_hawley_2015Our most popular new blog post of the year came from UNeMed’s newest team member, Amanda Hawley, PhD An intern at the time, Dr. Hawley had recently completed her doctorate in cancer biology, and offered advice to fellow scientists looking for alternate career options. Her key recommendation: Challenge yourself with new experiences outside your comfort zone. You might be surprised with what you learn about yourself. Since then Dr. Hawley has been promoted to a full-time postdoctoral position with UNeMed.

6. Radux begins prototype testing

Radux, a new company built on a UNMC invention, is the most recent in a long line of startups that has benefited from the University of Nebraska’s Proof of Concept grant funding program. Radux used the cash to build its first working prototypes of devices made to protect physicians from harmful radiation and other injuries that can occur while performing fluoroscopic procedures. Radux was founded by UNMC interventional radiologist Greg Gordon, M.D.

7. Leuenberger says goodbye

Don Leuenberger

Don Leuenberger raises a special gift he received in recognition of 24-years of dedicated service since UNeMed was founded in 1991.

Although UNMC bade farewell to Vice Chancellor Don Leuenberger in 2015, the “Godfather of UNeMed” is expected to continue his role as chairman of the Board of Directors. Leuenberger helped create UNeMed 24 years ago, and was recognized for his contributions at the 2015 Shareholder Meeting in August. The Shareholder Meeting also highlighted key successes for UNeMed during the 2015 fiscal year, including $1.11 million raised in sponsored research.

8. Markin, Boedeker land national awards

boedeker_compositeTwo more UNMC inventors earned national recognition with awards, most recently on Dec. 16 when Rodney Markin, M.D., was named a Fellow of the National Academy of Inventors. “Rod is a rare breed,” said Michael Dixon, PhD, president and CEO of UNeMed. “It’s uncommon to have a skilled clinician who also has such a keen understanding of business and what it takes to develop a product. Not only is he a prolific inventor with 35 patents, but he’s also helped turn those ideas into products – products that have built startup companies or have sold widely in multinational companies.”
In September, Ben Boedeker’s suction catheter won a 2015 EMS World Innovation Award.

9. Now accepting apps

unemedappserviceIn May, UNeMed announced that its services now also cover smartphone and tablet applications. UNeMed can help provide or find resources for further development while securing any intellectual property associated with the software. As a registered publisher at iTunes and Google Play, UNeMed can also publish an app to the most common marketplaces.

10. Prommune starts vaccine trials in pigs

One of UNeMed’s most long-standing startups companies, Prommune, took an important step forward in 2015. After bringing in a new CEO, Prommune quickly lined up a trial for its vaccine against the H1N1 virus, commonly referred to as the Swine Flu. Early results are not yet complete, but Prommune’s inventor-founder Sam Sanderson, PhD, hopes to develop the vaccine for use in pigs before expanding the technology into other uses.

Honorable Mention:

WEB_agnes_lenagh_2015WEB_jeff_andersen_2015WEB_qian_zhang_2014One of our most popular posts from 2015 announced the new status of Qian Zhang, Ph.D., UNeMed’s International Technology Development Specialist. Already holding a doctorate in cancer biology and an MBA, Dr. Zhang passed the U.S. Patent Bar, qualifying her as a registered patent agent who can draft, file and prosecute patent applications. UNeMed also announced in 2015 the addition of Jeff Andersen as contracts specialist and the promotion of Agnes Lenagh, PhD, to a permanent position as a licensing specialist. Andersen filled an unexpected vacancy after the October 2014 passing of Jack Mayfield. Dr. Lenagh first joined UNeMed in 2011 as an intern then shifted to a postdoctoral position before accepting her current position.

Classics

Several posts from previous years remain popular and relevant, particularly those that focus on day-to-day operations and legal issues associated with intellectual property.
1. Importance of Technology Transfer
2. How to Determine Who is an Inventor on a Patent: Unraveling Inventorship vs. Authorship
3. Technology Transfer 101: Defining Research Commercialization
4. Safeguarded in the Vault: How Trade Secrets Work

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Markin named a Fellow of the National Academy of Inventors

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by Tom O’Connor, UNMC

Rodney Markin - Pathology

OMAHA, Neb. (Dec. 16, 2015)—Rod Markin, M.D., PhD, chief technology officer and associate vice chancellor for business development at the University of Nebraska Medical Center, has been named a Fellow of the National Academy of Inventors (NAI).

Election to NAI Fellow status is a high professional distinction accorded to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development, and the welfare of society.

The 168 named this year bring the total number of NAI Fellows to 582.  The honorees join a prestigious list of past Fellows that include 27 Nobel Laureates, 80 presidents and senior leaders of research universities and non-profit research institutes, and 27 inductees of the National Inventors Hall of Fame.

Dr. Markin has been associated with UNMC for more than 35 years. He earned his medical degree from UNMC in 1983 and his doctoral degree from the University of Nebraska-Lincoln in 1980. He joined the UNMC faculty in 1986.

He was named to his current position in 2011. Among his duties, Dr. Markin works closely with departments to plan major equipment purchases and make sure that utilization justifies cost. He looks for opportunities for departments to better coordinate their use of equipment and seeks potential new uses for information systems and telemedicine.

In 2010-11, Dr. Markin served as interim dean of the UNMC College of Medicine. Prior to this, he was the David T. Purtilo Distinguished Professor of Pathology and senior associate dean for clinical affairs in the College of Medicine. He also served as president of UNMC Physicians, the physician practice group for UNMC, from 1997 to 2010.

Dr. Markin is one of the most prolific inventors at UNMC. In 2009, he received the Lifetime Achievement Award from UNeMed Corporation, UNMC’s technology transfer company, for his innovative work in transforming the clinical laboratory through technology.

“Rod is a rare breed,” said Michael Dixon, PhD, president and CEO of UNeMed. “It’s uncommon to have a skilled clinician who also has such a keen understanding of business and what it takes to develop a product. Not only is he a prolific inventor with 35 patents, but he’s also helped turn those ideas into products – products that have built startup companies or have sold widely in multinational companies.”

The NAI Fellows will be inducted on April 15, as part of the Fifth Annual Conference of the National Academy of Inventors in Alexandria, Va. Fellows will be presented with a special trophy, medal, and rosette pin.

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Scientific Research: Frankly my dear, you should give a damn!

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by Amanda Hawley, UNeMed | December 1, 2015

Trying to convey the significance of science without proper communication skills is like asking a friend to assemble an IKEA chair, but giving them the instructions through interpretive dance.

Good luck.

Publishing and presenting scientific discoveries in only field-specific venues will limit the impact and greater purpose of publicizing these advances.

But why should science enthusiasts give a damn?

Information provided by media influences the opinions and ideologies of the public, which in turn shapes the political climate. The public’s perception of science and research—be it positive or negative—effects the decision makers in our nation’s capital.

Science supporters need to ignite a change in the public perception to prioritize education and research programs. One way to accomplish this shift is by improving the current strategies of informing and educating the general population.

Learning of new discoveries should not require an advanced degree in science or a decoder ring to translate scientific jargon.

Communicating these scientific advances should be applicable to all. And I mean all—right down to story time, sitting crisscross-applesauce surrounded by sticky fifth-graders.

If researchers are frustrated with the lack of funding or diversity within the sciences, perhaps it’s time to look in the mirror. The public’s lack of scientific understanding and appreciation stems from the negligent and an improper education.

Vocal, non-science experts create distrust and doubt, misleading the public away from science, as seen in the debates on vaccines and global-climate change.

A well-known U.S. scientist Neil deGrasse Tyson, PhD, said in a November 2007 Point of Inquiry interview: “How is it that access to science could be so high, yet it appears that science literacy in the population has made only marginal gains, if at all? Some would say its reverted to superstitious over the rational analysis of the real world in which we live.”

He added: “The more I recognize that things might be going backwards, the more I would have to admit that I am failing in what I am trying to do…create some increased level of science literacy in the electorate.”

Despite the enormity of resources just a click away, an inaccurate public perception of science is the annoying pop-up windows you can’t close.

Adam Ruben, PhDAdam Ruben, PhD, from “Outrageous Acts of Science” on the Science Channel, gave a talk during UNMC’s 2015 Innovation Week titled “Public Perception of Science.” He listed examples of the public’s ill-informed response to scientific discovery like cloning animals, vaccines, and the joke campaign against dihydrogen monoxide (a.k.a. water, H2O).

Dr. Ruben explained how the portrayal of scientific discovery can be alluring to audiences, yet entirely misleading. This deception further weakens the relationship between scientists and the public.

Why are scientists generally identified as being unapproachable, elitist, or stereotyped as mad? Sorry scientists, we are as relatable as porcupines and pineapples.

The stereotype of scientist was no better depicted by a class of seventh-graders. The class was asked to draw and describe a scientist before and after meeting an actual researcher. In the first drawing, the majority of children depicted a nerdy-looking, bald man wearing a white lab coat. After meeting an actual scientist, they drew normal-looking people without the stereotypical identifiers.

Perhaps the issue of science illiteracy boils down to the public’s inability to relate to scientists or connect to science overall.

A common problem in many relationships is improper communication.

With the current communication strategy applicable to only a miniscule percentage of the population, I fear scientific researchers will further become estranged from the public and hinder the support of scientific innovation.

So frankly my dears, you all should give a damn!

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UNeMed signs deal with H4 Technology for better healthcare

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contractsby Charles Litton, UNeMed

OMAHA, Neb. (November 17, 2015)—Officials today formally announced a new partnership that could lead to more productive deals for software-based biomedical innovations developed at the University of Nebraska Medical Center and Nebraska Medicine.

H4 Technology, an Omaha-based software and analytics firm, entered a joint licensing agreement with Nebraska Medicine and UNeMed, the technology transfer arm of UNMC, to further develop a data-based management program for preventing and treating pressure ulcers—commonly known as bed sores. If the pressure ulcer application, called the Nebraska Matrix, progresses as expected, then H4 and UNeMed will likely expand the partnership to include similar UNMC inventions, officials said.

“I’m excited for the partnership with UNeMed because they are the perfect partner to further our mission to transform healthcare through technology,” H4 Technology president, Chris Henkenius, said. “We’re anxious to get started, and further this relationship for years to come.”

Henkenius first became aware of UNeMed during the 2015 Big Omaha convention—a massive annual networking event that brings together a wide swath of the regional entrepreneurship community. Kody Schrader, Senior Director of Entrepreneurship and Innovation with the Greater Omaha Chamber Commerce, introduced Henkenius to UNeMed president and CEO Michael Dixon.

“Kody pulled me aside and said, ‘Here’s some guys you should know,'” Dixon said. “Without Kody and Big Omaha, this technology and license probably never happens. I was enthusiastic from the start because H4 does exactly what we need.”

H4 Technology focuses on healthcare applications that are powered by advanced data integration, data storage and analytics. For the bed sore application, or Nebraska Matrix, H4 will use a protected algorithm formulated by UNMC associate professor Janet Cuddigan, R.N., PhD, to integrate healthcare data services with known best practices for treating and preventing pressure ulcers.

The result is a personalized care program for each individual patient based on their risk level for developing painful bed sores—which can lead to dangerous infections, longer hospital stays and increased costs.

But more than that, the base programming behind Nebraska Matrix has the potential to serve as a template for a number of different applications, said Chief Marketing Officer and H4 Technology co-owner, Craig Christenson.

“What we really like about the technology is its potential as a template for other hospital acquired conditions,” he said. “Analyzing outcomes to a specific care coordination plan is big for hospitals in monitoring, managing and reducing the risk of numerous conditions.”

Getting the Nebraska Matrix running will open the door to further development of other UNMC healthcare data applications that could include: Building a platform for managing and minimizing hospital acquired infections, and setting up another program that streamlines the process of coordinating emergency procedures when a patient’s heart stops beating.

“We’re excited about the opportunity to work with these products,” Christenson said, “because the need is there.”

“If we can do the analytics behind the programs, then we can improve outcomes,” he added.

— — —

About UNeMed:

UNeMed Corporation is the technology transfer and commercialization office (TTO) for the University of Nebraska Medical Center. UNeMed serves all UNMC researchers, faculty and staff who develop new biomedical technology and inventions, and strives to help bring those innovations to the marketplace.

About H4 Technology:

H4 Technology, a Nebraska based, consulting and application development company with over 15 years of providing technology solutions for the healthcare field. H4 Technology’s roots are in Health Information Exchange, Accountable Care Organization, and product development. They have also helped implement nine statewide and three regional HIEs, as well as numerous ACOs, HIOs, and hospital systems.

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Hawley named UNeMed postdoc

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LO_amanda_hawley_2015OMAHA, Neb. (November 1, 2015)—Amanda Hawley, PhD, has been promoted from intern to a full-time postdoctoral position as a licensing associate with UNeMed, the technology transfer and commercialization office at the University of Nebraska Medical Center.

“Dr. Hawley has been a great addition to the UNeMed family,” UNeMed president and CEO Michael Dixon said. “We knew pretty quickly after she started here that we wanted to keep her around for a long time. Her kind of talent, skills and energy don’t come along every day.”

The promotion and full-time status expands her role of evaluating, marketing, and seeking partnerships for new inventions, cures, treatments and medical devices developed at UNMC.

UNeMed’s mission is to help UNMC researchers, faculty and staff move innovations and ground-breaking discoveries beyond the laboratory and into the marketplace. Dr. Hawley joins UNeMed’s talented stable of licensing experts who work every day to advance UNMC’s new discoveries into the future cures and treatments that might one-day affect millions around the world.

“It’s a rewarding and stimulating position,” Dr. Hawley said. “With the new position, I feel a sense of peace and like I can make an impact.”

A native of Portland, Ore., Dr. Hawley is the daughter of Jay and Debbie Lakamp, and a 2004 graduate of Sunset High School. She went on to Western Oregon University in Monmouth for her biology degree in 2009. Dr. Hawley received her doctorate in cancer biology from UNMC in 2014.

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Boedeker Suction Catheter wins innovation award

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by Tyler Mueller, UNeMed

OMAHA, Neb. (Sept. 24, 2015)—The Boedeker Suction Catheter, a University of Nebraska Medical Center innovation, was a winner of a 2015 EMS World Innovation Award, presented during the EMS World Expo in Las Vegas.

Invented by Ben Boedeker, M.D., PhD, professor of anesthesiology at the University of Nebraska Medical Center, the Boedeker Suction Catheter is used with a video laryngoscope “blade,” the device physicians use to open a patient’s airway, to help clear obstructions of the camera view or supplement oxygen during the procedure.

Developed more than a century ago, the Yankhauer suction tip remains the most common choice, but it does not maintain a clear view for the camera, particularly while intubating a trauma patient. The Boedeker Suction Catheter complements the Yankhauer design as a solution to remove excess fluids or deliver oxygen during trauma intubations.

The Boedeker Suction Catheter is disposable and fits into the blade’s curved channel, keeping it out of the way and making it easier for a physician to insert an endotracheal breathing tube. The design can be customized to fit any manufacturer’s blade, and the user can easily control the amount of oxygen or suction.

The EMS World Innovation Awards recognize the industry’s most innovative technologies of the year on display at the Emergency Medical Services World Expo held this year on Sept. 15-19. Award recipients were selected by a panel of judges from the EMS World Expo Faculty and EMS World Editorial Advisory Board.

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Demo Day 2015 highlights UNMC innovations

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by Tyler Mueller, UNeMed

OMAHA, Neb. (October 21, 2015)—A combination of six technologies and startup businesses were presented to an estimated audience of 65 during Demo Day.

Part of UNeMed’s Innovation Week, Demo Day features new up-and-coming projects in the science and healthcare industry. Watch the presentations on YouTube.

Jeff Hanson of Aviture started the presentations with PortCas, a portable laparoscopic surgical simulation platform developed at the University of Nebraska Medical Center.

Jeff Hanson

The PortCas, or Portable Camera Aided System, is designed to train medical students in laparoscopic surgery through the use of a simulation. Users operate laparoscopic tools in a space the size of a small suitcase to carefully set rings around pegs through a virtual interface similar to a video game. Users are scored on the speed and smoothness of each hand. A web interface also allows advisors to track a user’s progress and offer feedback.

Joseph Sui“The idea of PortCas is pretty basic,” said Joseph Siu, PhD, who is working with Hanson on the PortCas. “If we can move a humongous, $100,000 simulator, move it into tiny boxes, and make it cheap enough for every medical student in the world to have one, then we’ve met our goal.”

The PortCas is one of the inventions being developed by Aviture through The Garage, an environment setup to assist web-based startups into successful companies.

Prommune Inc. CEO Sam Al-Murrani, PhD, presented a platform technology developed by Sam Sanderson, PhD, that boosts the immune system to fight disease and infections.

Sam Al-MuraniDr. Al-Murani said the technology is unique because it’s a naturally occurring protein, versatile, easy to manufacture and easy to store and use.

“It can be used in a myriad of ways with almost anything you can think of,” Dr. Al-Murrani said.

The technology isn’t designed to replace antibiotics but work in conjunction with them to enhance the response and fight infections and diseases.

The technology is currently in a clinical trial as a vaccine for pigs against the H1N1 virus, also known as the Swine Flu. Continued success in the animal market could eventually lead to human trials.

Qian ZhangQian Zhang, PhD, of UNeMed presented the Portable Laparoscope, an invention of Chandra Are, M.D.

The Portable Laparoscope is an all-in-one laparoscopic suite, emulating the process without the need for the dedicated space, other pieces of equipment, or multiple assistants. A typical laparoscopic operating room can cost up to $500,000.

The Portable Laparoscope is designed to help developing countries overcome the cost barrier, and allow laparoscopic procedures in remote locations where an operating room is inaccessible, such as the battlefield.

Evan Luxon presented Esculon, a medical device incubator, and Thoraguard, a product currently under development at Esculon.

Evan LuxonThoraguard is an innovative approach to the chest tubes used to drain fluids. The tubes are prone to clogging, causing Retained Blood Complex, which doubles the mortality rate, increases the length of stay in patients by about a week, and increases the costs to care for a patient by about $30,000. Larger tubes cut down on clogging but bring about a different set of problems, such as increased infections and damage to surrounding organs.

“These devices haven’t been updated in about 50 years,” said Luxon. “You can imagine what the state of cardiac surgery has done since then.”

Thoraguard, an automated add-on to current chest systems, uses the smaller tubes without the complications of clogging.

Valeriya KettelhutValeriya Kettelhut, M.D., PhD, presented a system to track infections in hospitals and other high-risk environments, such as transport centers, cancer centers, and long-term facilities.

The Tactical Biosurveillance, or TBios, is a system to map and alert users of high-risk environments.

TBios uses a web interface to visualize data that features a heat map overlay on a site-specific floorplan. With little more than a glance, interface helps facility personnel identify high-risk areas, patients or even rooms. The interface can even help them understand which workers might be at the higher risk to catch or further spread an infection.

Mike Draper, CEO of Center Ridge Holding LLC, presented CleanCore, an innovative cleaning technology that uses water infused with ozone gas for an environmentally-friendly cleaning solution.

Mike Draper“Think about how we use chemical today,” said Draper. “Our overuse of chemicals and anti-microbial products are contaminating ourselves, our water, our air, our ground, and creating new contaminants in our environment.”

Draper said CleanCore insignificantly easier to use. Instead of numerous chemicals for different surfaces and different handling and safety practices, CleanCore is a one-step, easy-to-use system.

Draper said one study predicted that if 20 percent of K-12 schools used CleanCore instead of traditional chemicals, it would offset the emission of over 58,000 vehicles for five years, lessen dependence on foreign oil by over 385,000 barrels, or provide enough energy to power the homes 56,000 homes for five years.

“That’s a city the size of Flint, Michigan, or Sioux City, Iowa,” Draper said.

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Kielian is the 2015 Innovator of the Year

Comments (1) Innovation Week, News, Success Stories

Tammy Kielian, PhD, Professor of Pathology, Dept. of Pathology and Microbiology, University of Nebraska Medical Center

by Tyler Mueller, UNeMed

OMAHA, Neb. (October 23, 2015)—Tammy Kielian, PhD, was named the “2015 Innovator of the Year” during UNeMed’s annual Research Innovation Awards Ceremony and Reception yesterday, before an estimated crowd of 208.

Hosted by UNMC’s technology transfer office, the awards ceremony is the culmination of Innovation and Research Week, a series of events to showcase and celebrate UNMC discoveries.

During the Innovation Awards, UNeMed honored all UNMC personnel who submitted a new invention, received a U. S. patent or licensed a technology. UNeMed also named a portfolio of inventions by Michael Wadman, M.D., and Thang Nguyen, M.S.N., A.P.R.N., as the “Most Promising New Invention of 2015.”

UNMC Professor of Pathology Tammy Kielian, PhD, (left)—seen here with doctoral student Megan Bosch—is UNeMed's 2015 Innovator of the Year for work against Juvenile Batten Disease and biofilm infections.

UNMC Professor of Pathology Tammy Kielian, PhD, (left)—seen here with doctoral student Megan Bosch—is UNeMed’s 2015 Innovator of the Year for her work against Juvenile Batten Disease and biofilm infections.

Dr. Kielian—honored in 2012 as the “Emerging Inventor”—is the first two-time winner of a major UNeMed award in the nine-year history of the program. Her work on a potential cure for Juvenile Batten Disease and treatments for S. aureus biofilms made her an easy choice for the top award in 2015, said UNeMed president Michael Dixon.

“Dr. Kielian is exactly the kind of scientist we love to celebrate during Innovation Week,” Dixon said. “Every day she and her team does what it takes to move the science forward, and help us push her research into the real world where it has a chance to not just save lives, but save families.”

Dr. Kielian and her team are approaching clinical trials on two approaches to fighting the as yet incurable Juvenile Batten Disease, a rare and always fatal childhood neurodegenerative disease. One approach treats the disease using an existing class of drugs, but the other approach, a gene therapy treatment, has potential as a cure.

In addition to her work against Juvenile Batten Disease, Dr. Kielian—the Choudari Kommineni, D.V.M., PhD, Professor of Pathology in UNMC’s Department of Pathology and Microbiology—developed a new strategy for targeting the immune system to help prevent and treat Staphylococcus aureus biofilm infections.

Michael Wadman, M.D., (left) and Thang Nguyen, N.P.

Michael Wadman, M.D., (left) and Thang Nguyen, M.S.N.

Dr. Wadman and Nguyen, who both work in UNMC’s Department of Emergency Medicine were awarded the “Most Promising New Invention of 2015” for their innovative concepts for better wound irrigation and oral airway management.

Together, the tandem developed an irrigation system that can adjust and maintain consistent pressure with enough solution to clean almost any wound. They are also working on a set of inventions that could help emergency care providers maintain keep clear a patient’s airway.

Roychoudhury

Roychoudhury

The Awards Ceremony concluded with the free iPad drawing, which was awarded to PhD student Shrabasti Roychoudury.

Other events featured during 2015 Innovation and Research Week included a full slate of seminars hosted by the Office of the Vice Chancellor for Research, which were aimed at helping research understand and better use all the resources at their disposal.

The week also saw for the first time a closer look at the new Interprofessional Experiential Center for Enduring Learning or iEXCEL. The hands-on exposition gave guests a glimpse at some of the world’s most advanced medical training and simulation technologies that UNMC will use to train future clinicians.

Brittney White, a cardiovascular tech in the Cardiac Catheter Lab at Nebraska Medicine, checks out on the 3D imaging tools during the iEXCEL Expo Tuesday, Oct. 20, 2015, during UNeMed's Innovation and Research WeeK.

Brittney White, a cardiovascular tech in the Cardiac Catheter Lab at Nebraska Medicine, checks out on the 3D imaging tools during the iEXCEL Expo Tuesday, Oct. 20, 2015, during UNeMed’s Innovation and Research Week.

Also new this year was Mission SimPossible, simulation contest between two groups of medical students that tested their abilities to diagnose, treat and mange a complicated medical situation. The Emergency Medicine Interest group won the top prize and the Family Medicine Interest Group was the runner-up.

UNeMed also hosted two events aimed at graduate students with a panel discussion about alternate careers in science away from the bench and more humorous look at academic science through the lens of Adam Ruben, author of “Surviving Your Stupid, Stupid Decision to Go to Grad School.”

Finally, UNMC Technology Demonstration Day entered its third year with six presentations about current UNMC technologies or collaborations that are currently approaching the marketplace.

Adam Ruben, PhD

Adam Ruben, PhD

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UNeMed boosts Nebraska to top 10 rankings

Comments (0) News, Success Stories

by Tyler Mueller, UNeMed

OMAHA, Neb. (October 21, 2015)—Citing UNeMed as one of its principle advantages, Nebraska was ranked ninth in the nation for its overall business climate and sixth for its overall transportation and trade, according to a new report by the U.S. Chamber of Commerce Foundation.

UNeMed was singled out as one of the companies responsible for Nebraska’s high rankings. The Business Innovation Act was also listed as a reason for Nebraska’s success. Passed in 2011, the Business Innovation Act helps companies with a variety of programs that offer grants, seed funds and other support.

The “Enterprising State” study ranks the top 10 states in more than 35 metrics, such as economic performance, transportation and trade, innovation and entrepreneurship, business climate, talent pipeline, high-tech performance, and methodology. The study focuses on highlighting and celebrating states that have excelled at creating policies and cultures that nurture innovation and entrepreneurs. U.S. annual GDP has grown approximately 50 percent, attributed to surges in innovation by economists, according to the report.

A research base to develop new ideas, the successful transfer of knowledge to the marketplace, and an entrepreneurial culture are some of the elements required to build a tech-based economy, according to the State Science and Technology Institute.

The report highlighted that states are focusing on attracting high-tech firms because they typically bring in higher-paying jobs, create additional, non-tech related jobs, and can be connected and located almost anywhere via the internet. Despite few companies operating in the technological field, the report stated more and more businesses rely on cutting-edge technology from tech-focused companies to compete.

 

Business Climate

  1. South Dakota
  2. Alaska
  3. Wyoming
  4. Florida
  5. Nevada
  6. North Dakota
  7. Utah
  8. Idaho
  9. Nebraska
  10. Montana

 

Transportation and Trade

  1. Louisiana
  2. South Carolina
  3. Texas
  4. Georgia
  5. Utah
  6. Nebraska
  7. Tennessee
  8. Washington
  9. Nevada
  10. Alabama

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Raw sewage, unicorns and grad school

Comments (0) Innovation Week, News

rubenby Tyler Mueller, UNeMed

OMAHA, Neb. (October 20, 2015)—Featured speaker Adam Ruben, PhD, joked about the grueling, thankless, tiring process of obtaining his PhD, and why he still didn’t completely hate it.

As part of UNeMed’s Innovation Week, Dr. Ruben—author of “Surviving Your Stupid, Stupid Decision to Go to Grad School”—entertained an estimated audience of 80 with his negative experiences in graduate school, but also offered a bit of serious advice for careers outside the lab.

Dr. Ruben first marveled at UNMC’s graduate program, which he called the “unicorn of grad school” because students here typically finish their programs within five or six years. “That’s not normal,” he said. “You guys are in an unusually good place.”

He then relayed a story about his sixth-year in grad school, where his advisor demanded data for a seminar in three days. Dr. Ruben said he worked 63 hours over three days to meet the deadline, which left only three hours for sleep each night. The problem was when he got home the first night, his basement-level bedroom was flooded with raw sewage. Without enough time or resources to resolve the reeking filth in his bedroom, Dr. Ruben continued his work—and got what sleep he could in his flooded room.

He made the deadline, but when it came time to present Dr. Ruben’s data during the seminar, the advisor did not even include in the presentation.

The entire experience, he felt, perfectly summed up graduate school.

“And so, it was with that, that I decided to write this book,” Dr. Ruben said.

Dr. Ruben read passages from his book, poking fun at various aspects of graduate school, including the exhausting process of having his advisor and committee members all want to put their own spin on his thesis, and all the ridiculous ways students try to remember ridiculous amounts of knowledge.

Dr. Ruben urged students to do as many things as possible, even when they don’t seem very lucrative. Dr. Ruben judged high school science fairs. While he didn’t take away any career opportunities from it, it was something he enjoyed and learned from. Doing something might lead to something better, Dr. Ruben said.

“Doing nothing will lead to nothing,” he said.

Dr. Ruben also advised students to be open to other careers.

“Academic scientists are told, ‘You have two choices: You can be a tenure-track professor or you can be a failure,’” said Dr. Ruben.

Dr. Ruben argued that wasn’t the case, listing off careers such as science writing, science advocacy, consulting, industry science, and teaching.

Those kind of careers are often a result from meeting people at events and other activities that fall outside graduate work. He said it was a low-percentage to make the right kind of connection so it was important to continually engage in the things you enjoy.

But when it comes to graduate work, Dr. Ruben stressed that students take the initiative.

“Don’t wait for someone to make you do the work,” said Dr. Ruben. “You have more control over your destiny than you think you do.”

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