Ajuba plays an important role in regulation of the kinase activity of AURKA/Aurora-A for mitotic commitment. Ajuba is a component of the IL-1 signaling pathway modulating IL-1-induced NF-κB activation and also plays a role in cadherin-mediated cell-cell adhesion and influences cell migration.
Epitope: Human Ajuba
Species: Human
Uses: WB, IF
Type: Mouse mAb
Publications: None

Epitope: Human ADA3
Species: Human
Uses: WB, IHC
Type: Mouse mAb
Publications: Mohibi S et al. J. Biol Chem (2012) v287: 29442-29456 ; Mirza et al. Breast Cancer Res Treat (2013) v137: 721-731; Mohibi S et al. J. Biol Chem (2015) V290: 28299-28310

Cadherins are integral membrane proteins that mediate calcium-dependent cell-cell adhesion.
Epitope: EC domain Cad11
Species: Human
Uses: WB, IP, IF
Type: Mouse mAb
Publications: None

Cadherins are integral membrane proteins that mediate calcium-dependent cell-cell adhesion.
Epitope: EC domain Cad11
Species: Human
Uses: WB, IP, IF
Type: Mouse mAb
Publications: None

Cadherins are integral membrane proteins that mediate calcium-dependent cell-cell adhesion.
Epitope: EC domain Cad11
Species: Human
Uses: WB, IP, IF
Type: Mouse mAb
Publications: None

Desmogleins are a family of cadherins that play a role in the formation of desmosomes that join cells to one another.
Epitope: N-terminal region of extracellular domain 1 of desmoglein 2 and a region that is at the fusion between EC1 and the proregion.
Species: Human
Uses: WB, IF
Type: Mouse mAb
Publications: Keim S et al (2008) Hybridoma 27 (4) 249-258

Desmogleins are a family of cadherins that play a role in the formation of desmosomes that join cells to one another.
Epitope: C-terminal region of extracellular domain 1 of desmoglein 2
Species: Human
Uses: WB, IF
Type: Mouse mAb
Publications: Keim S et al (2008) Hybridoma 27 (4) 249-258

Desmogleins are a family of cadherins that play a role in the formation of desmosomes that join cells to one another.
Epitope: C-terminal region of extracellular domain 1 of desmoglein 2
Species: Human
Uses: WB, IF
Type: Mouse mAb
Publications: Keim S et al (2008) Hybridoma 27 (4) 249-258

Desmogleins are a family of cadherins that play a role in the formation of desmosomes that join cells to one another.
Epitope: N-terminal region of Extracellular domain 1 of desmoglein 2 and a region that is at the fusion between EC1 and the proregion
Species: Human
Uses: WB, IF
Type: Mouse mAb
Publications: Keim S et al (2008) Hybridoma 27 (4) 249-258

DHHC5 is a member of the DHHC family of palmitoyl-cyl transferases. These enzymes catalyze the addition of palmitate onto cysteine residues of target proteins.
Epitope: Human DHHC5
Species: Human
Uses: WB
Type: Mouse mAb
Publications: None

DHHC5 is a member of the DHHC family of palmitoyl-cyl transferases. These enzymes catalyze the addition of palmitate onto cysteine residues of target proteins.
Epitope: Amino acids 40-150
Species: Human
Uses: WB, IF
Type: Mouse mAb
Publications: None

Fibroblast growth factor receptor 4 (FGFR4), also known as CD334, is a member of the fibroblast growth factor receptor family and a cell surface tyrosine kinase containing three immunoglobulin-like domains. FGFR4 is widely expressed in many tissues including the intestine, muscle, heart, cornea, retina, and pancreas, with highest expression in lung and kidney. FGFR4 binds acidic fibroblast growth factor and ligand binding induces mitogenesis and differentiation. FGFR4 is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.
Epitope: Human FGFR4
Species: Human
Uses: WB, IP, IF
Type: Mouse mAb
Publications: None

LGR6 is a glycoprotein hormone receptor that is a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily.
Epitope: Human LGR6
Species: Human
Uses: WB
Type: Mouse mAb
Publications: None

Microtubule-associated serine/threonine-protein kinase-like (MastL) has been associated with thrombocytopenia and thrombocytopenia 2. MastL is a serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and mmaintenance. Following DNA damage, MastL is also involved in checkpoint recovery by being inhibited. May be involved in megakaryocyte differentiation.
Epitope: C-terminus
Species: Human
Uses: WB, IHC
Type: Mouse mAb
Publications: None

Mucin-4 (MUC4) is a mucin protein and a major constituent of mucus. MUC4 plays various roles in the progression of cancer, particularly due to its signaling and anti-adhesive properties which contribute to tumor development and metastasis. MUC4 is also important in other diseases such as endometriosis and inflammatory bowel disease.
Epitope: Tadem Repeat Domains
Species: Human
Uses: WB, IP, IHC
Type: Mouse mAb
Publications: Moniaux N et al (2004) J Histochem Cytochem 52 (2) 253-261

Sodium-hydrogen exchange regulatory cofactor NHE-RF2 (NHERF-2) is also known as tyrosine kinase activator protein 1 (TKA-1) or SRY-interacting protein 1 (SIP-1). NHERF-2 acts as a scaffold protein connecting plasma membrane proteins with members of the ezrin/moesin/radixin family, linking them to the actin cytoskeleton and regulating their surface expression.
Epitope: AA 149-231
Species: Human
Uses: WB, IP, IF
Type: Mouse mAb
Publications: Theisen C et al (2007) Mol Biol Cell 18 (4) 1220-1232

OTK18 is classified as a transcription factor as it contains 13 C2H2-type DNA binding zinc finger motifs. C2H2 zinc finger motifs are capable of binding to a wide range of DNA sequences, including the HIV-1 LTR. This human immunodeficiency virus (HIV)-inducible zinc-finger protein reduces progeny-virion production in infected human macrophages.
Epitope: OTK 1-178
Species: Human
Uses: ELISA, WB, IHC
Type: Mouse mAb
Publications: Buescher J et al (2008) J Neuroimmune Pharmacol 3 (4) 230-235

A member of the p53 familyof transcription factors, p63 plays a key role in the regulation of epithelial proliferation and differentiation.
Epitope: Human p63
Species: Human
Uses: WB
Type: Mouse mAb
Publications: Buescher J et al (2008) J Neuroimmune Pharmacol 3 (4) 230-235

Plakophilins are proteins of the cytoskeleton.
Epitope: AA 235-726
Species: Human
Uses: WB, IP, IF
Type: Mouse mAb
Publications: Sobolik-Delmaire T et al. (2010) J Invest Dermatol 130 (11): 2638-46

Plakophilins are proteins of the cytoskeleton.
Epitope: AA 1-350
Species: Human
Uses: WB, IP, IF
Type: Mouse mAb
Publications: Sobolik-Delmaire T et al. (2010) J Invest Dermatol 130 (11): 2638-46

Plakophilins are proteins of the cytoskeleton.
Epitope: AA 1-308
Species: Human
Uses: WB, IP, IF
Type: Mouse mAb
Publications: None

Desmogleins are a family of cadherins that play a role in the formation of desmosomes that join cells to one another.
Epitope: Proregion human desmoglein 2
Species: Human
Uses: WB, IF
Type: Mouse mAb
Publications: Keim S et al (2008) Hybridoma 27 (4) 249-258

Desmogleins are a family of cadherins that play a role in the formation of desmosomes that join cells to one another.
Epitope: Proregion human desmoglein 2
Species: Human
Uses: WB, IF
Type: Mouse mAb
Publications: Keim S et al (2008) Hybridoma 27 (4) 249-258

Desmoplakin is a component of desmosomes, the intercellular junctions that tightly link adjacent cells. Desmoplakins anchor intermediate filaments to desmosomal plaques.
Epitope: 20B6
Species: Human
Uses: WB, IP, IF
Type: Mouse mAb
Publications: Sobolik-Delmaire T et al. (2006) JBC 281 (25) 16962-16970

Desmoplakin is a component of desmosomes, the intercellular junctions that tightly link adjacent cells. Desmoplakins anchor intermediate filaments to desmosomal plaques.
Epitope: 23F4
Species: Human
Uses: WB, IP, IF
Type: Mouse mAb
Publications: Sobolik-Delmaire T et al. (2006) JBC 281 (25) 16962-16970

α-catulin is an α-catenin-related protein that shares structural similarities with cytoskeletal linker proteins and facilitates Rho signalling.
Epitope: Human α-catulin
Species: Human
Uses: WB
Type: Mouse mAb
Publications: None

Epitope: Catalytic domain (1-320)
Species: Human
Uses: WB, IHC
Type: Mouse mAb
Publications: Sato S et al. J Neurosci (2008) v28: 14511-14521 ; Xu J et al. FASEBJ (2010) v24: 2904-2915; Asai H et al. Am J Pathol (2014) v184: 808-818